QH CC#68 - Page 6

Differential diagnosis
Paranoid Personality Disorder can involve, in response to
stress, very brief psychotic episodes (lasting minutes to hours).
If long-lasting the disorder may develop into delusional
disorder or schizophrenia . Individuals may also be at greater
than average risk of experiencing major depressive disorder ,
agoraphobia, obsessive-compulsive disorder or alcohol and
substance-related disorders . Criteria for other personality
disorder diagnoses are commonly also met, such as: [9]
schizoid personality disorder
schizotypal personality disorder
narcissistic personality disorder
avoidant personality disorder
borderline personality disorder

Treatment
Because of reduced levels of trust, there can be challenges in
treating PPD. However, psychotherapy, antidepressants ,
antipsychotics and anti-anxiety medications can play a role
when an individual is receptive to intervention.

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Epidemiology
PPD occurs in about 0.5%–2.5% of the general population. [4]
[9] It is seen in 2%–10% of psychiatric outpatients. It occurs
more commonly in males. [9]
A large long-term Norwegian twin study found paranoid
personality disorder to be modestly heritable and to share a
portion of its genetic and environmental risk factors with
schizoid and schizotypal personality disorder.

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