I actually missed a detail since I ff watched the Friday episode. But Commissioner and Malhar go to investigate Manjekar's house and find some evidence there. I feel evidence will point to Kalyani and maybe Nal Emporium.
And actually, I feel that Param may not be the US client. I feel he could be the politician that Malhar is guarding or someone else that may come up in the investigation cause in the BTS, Commissioner, Malhar, and Kallu are there talking to him. I also feel he will be the surprise villain at the end of the track and will pretend to be good for the time being.
And finally, Kalyani being caught in the tempo with the drugs is the final piece of the incriminating evidence. Commissioner will be sure that Kalyani is the drug peddler that her husband was after. Kalyani will beg Malhar to let it go, but he will choose duty and Kalyani will escape from there, accident, and then be deemed missing.
I think Commissioner will be suspicious that Malhar helped Kallu run away. So in the BTS with Anu, Kaka, and Malhar in some mela/pooja, seems that they are looking for someone, I feel think will be Kalyani. I also feel Commissioner will follow Malhar there due to her suspicions.
So memory loss I feel is the most likely option from there. And like of Minnie's story. Param finds her and knows who she is but he doesn't bring her back to her family cause of trauma and she believes he is her husband. If CVS do the addition of pregnancy, it will an added health issue, so he kept her with him.