Veer admits his role in Radhe's death. He also learns what Sunaina said/did to Krishna. Krishna, upon learning the truth, divorces Veer, because she cannot bear to be married to the man who killed Radhe, and also someone who left an innocent man to die in the street. She also puts Sunaina in her place (respectfully, in Krishna's own way) and tells her that she was selfish - in trying to protect her own son, she caused another mother to lose her son (I really, really need Krishna to say this dialogue to Sunaina).
Heartbroken, and having lost faith in love and marriage, Krishna leaves for London to finish her studies. Post-leap, we have Krishna returning to Kanpur to take over the hospital (let's assume someone else was running it for her in between). Around the same time, Veer is released from jail. He wants to approach Krishna, still loves her dearly, but he also respects her wish to be apart from him and tries to stay away from her. But destiny will keep forcing them together - maybe through the hospital, saving someone's life together (since they're both doctors) - and the love between them gradually blooms back to life.
Krishna slowly starts to realize that Veer truly is a good man who made a terrible mistake in his life, but that mistake doesn't mean that he's not a good person or not worth loving. And Veer will have his own journey to work through. He used to say that he deserves a good person like Krishna as his wife, but now he will doubt that. He won't have forgiven himself for causing her such pain, and he won't believe that he deserves her. Krishna, by seeing the good in him, will help him find it in himself.
I can see Krishna and Nayani staying connected during the time of the leap, because I think those two have truly formed a bond. I'm not sure what Sunaina's relationship will be with both of her children once they learn her role in everything. On one hand, I could see Veer not forgiving her for everything she did to Krishna - Veer does not forgive and forget easily. But on the other hand, he has always cared for and supported his mother, so it's hard to see him stop doing that.
Shukla's fate is also questionable. I don't think we would see this modern look of his bahus if he's still around. My hope is that he also ends up in jail when Veer does. I kinda don't want them to kill off his character (despite Bua's curse) because he's the villain we love to hate. I don't think any other villain can compare!