SHAH RUKH KHAN AS JAI VARMA / MICHAEL:Living two different lives, and doesn't even know about it. As Jai Varma, SRK plays a neurotic accountant working for Sharma Limited by day. All that changes when dawn hits and he changes into the cool womanising, but very aggressive Michael.
ABHISHEK BACHAN AS ANAND BAKSHI:A new journalist trying to find an interesting story to make a mark in the journalism world. Lives in an apartment accross Jai/Michael. They suddenly bump into each other one day, and Anand finds his story.
RANI MUKHERJEE AS SHALINI SHARMA:Quite intelligent like her father with a very feminist attitude. She dislikes all men who approach her and think they are "dogs, out to get one thing" Her father tells her she reminds him of her mother.
PREITY ZINTA AS KIRAN REDDY:Full time nurse assisting patients in a mental institute. She loves her work and loves to help people. It was daily routine for her until one day, a new patient comes in.
ARJUN RAMPAL AS Dr.VIKRAM CHATTERJEE:A doctor who majored in psychology and helps patients in a mental institute. His theory is that "no one is mental, but just misunderstood
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