Okay, I know IshRa fans will tell me I'm going over-board and bashing Ishita after reading my title. Then please read the quote I sated, Ishita said that to her doctor. If you in any way think this honest confession of Ishita suggests that she's in love, I've nothing to say.
You may say she'll be desperate to consummate her marriage with Raman. But it will surely look like she's got affected by Shagun's words and wanted to prove her wrong. The big c won't be out of love from Ishita's side, it will be a process to prove her point that she's not a governess to Raman.