No, actually, Kis Desh is one of the better shows about keeping characters in place. At least no major members of the family are missing YET... Alhough, I think I feel most sorry about the mamu ka other beta. His brother seems so... incomplete without them. It's like half the wallpaper is gone from the background (because I honestly think that's what their role is... wallpaper. Or saying "Prem bhaiya" or "bhabhi" once every few months.)
I've watched other bt shows, and there are disappearances FAR worse than this, especially if there is a generation leap. Usually, the explanation given is that the characters have gone abroad, or we are supposed to assume they have just died... But, honestly, I think they shouldn't keep complicating it with introducing so many characters. I mean, if they stick with the main juneja and maan families, we have plenty of storylines to go around. I also think that they can't afford to have extra actors on their payroll during these times.