If they don't butcher Anu in the sense that he does something that questions his love for her, like not accept her pregnancy or mistreats her in this stage, I don't think Pre with anyone else will be accepted.
If they give memory loss to Anu and Pre moves on with Bajaj or anybody else then maybe it could work, if Anurag is still given the same amount of focus and his own story of falling in love with someone else as a new story for him altogether because in every sense it would be a new fresh beginning for him. I personally don't have a problem with that if a new second female lead is also brought in. But then I don't want the soulmate story in that sense. Anu and Pre should start over with different people to be with these new partners from there on and fully in love with them and no hereafter for Anupre....After all what's the use of that....It would be as pointless as it was last season.....After having lived with and loved different people, what soulmate story was there to extend it to hereafter?.....It was stupid then and it would be stupid now too in this case.
I think there might be a chance for Prejaj to work in this scenario.....Though for me it would be Anu's story if this happens. I would love to see him fall in love and go through a different journey with someone else after memory loss...BUT NOT KOMO the murderer.....A new positive character.....Komo can still be the villain in Anu's story with his new love.
But one think is for sure....THEY WOULD BE MAHA STUPID to let go of Parica amazing chemistry and take the story in this direction given how well they have worked till the entrance of Bajaj...
But if the makers are hell bent on taking this the season one way then atleast forget the soulmate story and hereafter, and go for two different stories for Anu and Pre in the next half....Because I don't think even Prejaj fans want Pre to be running between bajaj and Anu through out the series like last season. The minute Prejaj is established let them have their story separate from Anu and let Anu have a story different from Pre...
Just don't go for the mess of season one....Anu deserves his own story and a happy one too just like Pre got with Bajaj.
As for how long the story can run without Anupre, I seriously have my doubts on that given how things have worked so far.....*shrugs*
PS: Parica have AMAZING chemistry and ANUPRE2 story had a really good run till Bajaj so, I would still have that to fall back on if I wanted to watch more of Anupre2 in future too. Honestly these CVs would be idiots to let Anupre2 go and take the story in a different tangent....But I'll take it as long as Anu gets his own story this time and no hereafter for Anupre2 in that case.