Hi
Since i m a biology student i decided to make this topic, Also its my moral duty to spread awareness.
So because of some recent spoilers i decided to share some knowledge about wht sickle cell anemia is .
It is a Genetic Disorder. (Autosomal i.e. its not related to sex chromosomes )
It occurs at chromosome 11
Caused by point mutation at the 6th position of beta-haemoglobin chain .. in simple words one of the coded amino acid gets replaced which causes this disorder
.
Patients with heterozygous Sickle cell have resistance to malaria especially to the sp. P.Falciparum .. which is the most dangerous type of malaria
it is commonly seen in Africa. But it can be found anywhere else in the world
And the homozygous individuals die early .. they dont even reach their 20s
And the heterozygous individuals are only carrires and are normal otherwise.
Acc to the spoilers kunj has sickle cell i.e. he is a homozygous SC patient and these patients die early and dont survive to this extent. So this all doesn't make any sense to me.
In this disorder when then oxygen concentration in low the RBCs - Red blood cells change their shape to a shape sickle like .. and these sickle shaped rbcs are difficult to pass through blood vessels which can cause heart attack .. clots .. etc.. and also prone to rupture.
The changing shape of rbcs can be temporary if the oxygen levels come back to normal required in a particular duration of time. If not then this sickle shape remains permanent
Its a request to cvs .. If u guys dont have proper information about any medical condition then pls donot 00show it ..
Half knowledge is always dangerous!!!!
So i hope if cvs r planing this track then they show it with accuracy and dont show it medically irrelevant.
I hope its helpful ..
Edited by Misnomer - 9 years ago