Leukaemia - the facts..

Henna 786 thumbnail
20th Anniversary Thumbnail Stunner Thumbnail + 3
Posted: 19 years ago
#1

Hey

Seen as Raashi has Blood cancer formally known as leukeamia.. i was thinkin ill post a few facts on the illness.. as we ALL knw these are real facts and wat Ekta uses are her own facts 😆 dont get them mixed up hehe

Leukaemia is a type of cancer which affects the blood cells. In the UK, leukaemia is the 12th most common cancer in adults, affecting more men than women. It is the most common cancer in children.

Cancer

The building blocks of the body are cells, which normally repair and reproduce in a controlled process. With cancer, this process goes wrong and cells divide and grow in an uncontrolled way. The body is made up of many different types of cells, such as skin, nerve, muscle and blood cells. With leukaemia, it is white blood cells that are affected.

About leukaemia

White blood cells are produced by the bone marrow, the soft spongy centre of bones. They then pass from the bone marrow into the blood stream and lymph system. White blood cells are involved in various functions of the immune system (the body's defence system), which protects the body from infections. In leukaemia, some blood cells do not grow properly, but remain within the bone marrow and continue to reproduce in an uncontrolled way. These cells fill up the bone marrow and prevent it from making healthy white blood cells. This means the body is less able to fight off infections.

The bone marrow is also able to make other types of blood cells, such as red blood cells and platelets. Problems can result from a reduction in number of these cells. For example, a lack of red blood cells leads to anaemia, which can result in breathlessness and fatigue. A lack of platelets can lead to problems with the blood-clotting system, resulting in bruising.

Leukaemia is the most common cancer in children, but cancer is generally rare in children, and leukaemia affects nine times as many adults as children.

Types of leukaemia

There are many types of leukaemia, named depending on the type of white blood cell affected, and how quickly the disease develops. Only the common types are discussed here.

The two main types of leukaemia are acute and chronic. Acute leukaemia tends to affect younger people. The symptoms develop rapidly, and it can quite quickly become life-threatening if not treated. The most common form affects white blood cells called lymphocytes. This is called acute lymphocytic leukaemia (ALL).

Chronic leukaemia tends to affect older people. The disease gets worse slowly and has a more prolonged progression. With chronic leukaemia, the white blood cells are almost fully grown and normal when they enter the blood stream. They can function, but not as well as they should do. One type of leukaemia called chronic myeloid leukaemia (CML) affects a particular type of white blood cells called myeloid cells. It has two phases, a chronic phase that may last several years, during which symptoms develop slowly, followed by a more aggressive phase (accelerated phase), where symptoms become rapidly worse.

What causes leukaemia?

The cause of most cases of leukaemia is not known, although there are some risk factors that increase the chance of developing the disease. These include:

    a weakened immune system - this may be a result of drugs that suppress the immune system (such as those used for organ transplants), high doses of radiation (such as in radiotherapy for another cancer), or diseases that affect the immune system (such as HIV)
    age - chronic leukaemias are more common over the age of 40
    smoking
    certain genetic conditions, such as Down's syndrome
    previous chemotherapy for another cancer
    other blood disorders, such as aplastic anaemia, a rare condition where the bone marrow fails to produce blood cells correctly
  • contact with a chemical called benzene, one of the chemicals in petrol and a solvent used in the rubber and plastics industry

Symptoms of leukaemia

The symptoms of leukaemia vary greatly, depending on the exact type of disease and how advanced it is. Few or no symptoms may occur in the early stages, especially in people with chronic leukaemia. Many symptoms are vague, such as fever, headaches, weight loss and night sweats.

Symptoms of leukaemia may include:

    tiredness, breathlessness and pale skin (due to anaemia, a reduction in number of red cells in the blood)
    frequent infections that do not get better (due to reduction in white blood cells, which fight infection)
    abnormal bleeding from gums and cuts (due to a reduction in platelets which are important for normal blood clotting)
    increased bruising (due to platelet reduction)
    heavier periods in women (due to platelet reduction)
    nosebleeds (due to platelet reduction)
    abdominal pain, due to an enlarged spleen or liver
    swollen lymph glands (glands in the neck, groin and under the arms)
    bone pain, due to the pressure of cell build-up
  • swollen gums, and occasionally, swollen testicles

Diagnosis

Leukaemia can be diagnosed from a blood test to measure the number of blood cells and look for any abnormal cells. People with suspected leukaemia are referred to a specialist doctor, usually a haematologist (an expert in the treatment of blood disorders).

Other tests are often performed to investigate the type of leukaemia and how far it has progressed. These include blood tests, X-rays, CT scans, removal of bone marrow for microscopic analysis and genetic analysis of the abnormal cells. These tests are all very important because they help guide the treatment.

Diagnosis, investigation, treatment and follow-up for people with leukaemia usually takes place at specialist centres, in hospitals.

Treatment

The effectiveness of treatment for leukaemia depends on the type and stage of the disease. Acute leukaemia often goes into remission (the symptoms go away; the disease is under control but not necessarily cured). However, many people with acute leukaemia have a relapse (the disease returns).

Chronic leukaemias develop more slowly than the acute types, but respond less well to chemotherapy and are rarely cured.

Acute leukaemia

Acute leukaemia is treated with chemotherapy to destroy the abnormal cancer cells. Mixtures of drugs are given into a vein in a series of treatment courses.

Medicines are available which reduce the side-effects of chemotherapy such as nausea. Hair may fall out during treatment but it re-grows once the chemotherapy has stopped. Some people may be able to use "cold caps" which cool the scalp and help prevent hair loss.

If the leukaemia returns (relapses), intensive treatment may be given. This involves a bone marrow or a stem cell transplant. Bone marrow or stem cell transplants allow much higher doses of chemotherapy to be given.

Before transplantation, very high doses of chemotherapy and sometimes radiotherapy are given to destroy all the bone marrow, both abnormal and normal. This improves the chance of completely curing the leukaemia.

Then normal bone marrow cells, donated from a close relative or carefully removed from the person's own bone marrow, are infused into the bloodstream with a drip.

Stem cell transplant involves transplanting stem cells (the most basic type of cell, from which all types of blood cells develop), rather than bone marrow cells. Stem cells can be harvested (collected) from a leukaemia patient's own blood or from a donor. New alternatives, which are currently experimental, include harvesting stem cells from umbilical cord blood or placentas of new born babies.

Chronic leukaemia

Treatment for chronic leukaemia depends on its type and stage. Often treatment is not started unless there are symptoms. In the early stage, treatment aims to control symptoms by reducing the number of abnormal cells in the blood.

Biological therapy may be an option for certain types of leukaemia, such as chronic myeloid leukaemia (CML). This involves treatment with natural substances (such as a protein called interferon alfa that helps the immune system fight leukaemia).

As the condition becomes more advanced, treatment may consist of mild chemotherapy, blood transfusion and antibiotics for infections. Some evidence indicates that in chronic myeloid leukaemia, bone marrow transplantation can prolong life if performed during its chronic phase.

Another available treatment is monoclonal antibodies. Antibodies are proteins that are produced by certain cells in response to infection. They usually attach themselves to bacteria or viruses and help to destroy them. A type of specifically manufactured monoclonal antibody that recognises and selectively destroys leukaemia cells can be infused into the body. An example is alemtuzumab (MabCampath), which is used to treat chronic lymphocytic leukaemia (CLL).

Hope you are more awarre off the illness..

Henna x

Created

Last reply

Replies

19

Views

1.4k

Users

11

Likes

4

Frequent Posters

candy_floss88 thumbnail
20th Anniversary Thumbnail Voyager Thumbnail + 2
Posted: 19 years ago
#2
very intresting thx for sharing 😊
Henna 786 thumbnail
20th Anniversary Thumbnail Stunner Thumbnail + 3
Posted: 19 years ago
#3
according to the info i got from different websites.. it says that wen you are in the last stages you should have an operation then chemotherapy..

oh another glorious blooper 😆

Henna x
j&b84 thumbnail
19th Anniversary Thumbnail Navigator Thumbnail
Posted: 19 years ago
#4
thks henna.. for information on leukaemia really appricate ur work

👏
👏
👏
👏
👏
👏
ABCD thumbnail
Posted: 19 years ago
#5
Hi,
very informative ...I glad you put in so much effort to put the information together and share it on the forum. Being a leukaemia patient on chemo for the past four years I was a little disappointed ( mostly outraged!! ) to see the callous way in which the issue is being dealt. No wonder more patients die of fear of cancer than the disease itself.

Sharing some stats that I found out while trying to select the line of treatment for myself from the options available at the time...only 30% percent of all cancers are terminal, 30% can be completely cured while 40% can be effectively managed without changing the life expectancy of the patient :)

archangel thumbnail
20th Anniversary Thumbnail Dazzler Thumbnail
Posted: 19 years ago
#6
can you email this to Kekta mai
rani_rani thumbnail
19th Anniversary Thumbnail Explorer Thumbnail
Posted: 19 years ago
#7
thx for sharing... it;s really interesting 😊
Henna 786 thumbnail
20th Anniversary Thumbnail Stunner Thumbnail + 3
Posted: 19 years ago
#8
WOW u guys found it again..

aww thank you 😳 it did take me long 😆
its a nice feelin wen sumone acknowledges ur wrk..

Henna x
shaz81 thumbnail
19th Anniversary Thumbnail Rocker Thumbnail Engager Level 1 Thumbnail
Posted: 19 years ago
#9

Originally posted by: Henna 786

WOW u guys found it again..

aww thank you 😳 it did take me long 😆
its a nice feelin wen sumone acknowledges ur wrk..

Henna x

I;m taking ALL credit cause if i remember it was MY idea LAMO!!!!!

MWAH for hard work i hope you got A in assighment for this !!!

Chick XXX

Edited by shaz81 - 19 years ago
187176 thumbnail
Posted: 19 years ago
#10
can you find out about the treatments i wanna see raashis chances of suviving 😳

Related Topics

Top

Stay Connected with IndiaForums!

Be the first to know about the latest news, updates, and exclusive content.

Add to Home Screen!

Install this web app on your iPhone for the best experience. It's easy, just tap and then "Add to Home Screen".