Acting is a tough profession, more so even in modern days where feedback is instant. Person playing negative roles face criticism for their characters and need to take that in their stride. Ignore the people who go overboard.
Take the neighborhood 6:30 pm where the actor playing a negative character(he is famous in Marathi TV) is criticized, but shares all the memes and engages with the fans quite cheerfully.
Around 10 years back at an airport lounge few girls said quite loudly that they would not sit next to Prem Chopra cos' he might molest them. Prem Chopra would no doubt have been hurt by those words, but he handled everything calmly, even the girls later realized that they mixed reel and real they apologized and were taking photos with him. Just needs a calm head and patience
Ultimately the other actors would be affected by this, since their acquaintances will be questioning them.
If fans are bullying some actor due to the character he/she play then they have to be called out.