Urgent - multiple choice in Genetics

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Posted: 13 years ago
#1
Anybody with knowledge of Genetics? To help a student, I urgently need answers to this questions.

1. A heterozygote has a 10% fitness disadvantage relative to wildtype homozygotes. The mutant homozygote has a 20% fitness disadvantage. What do you predict after many generations have passed?
A) Fixation of the mutant allele
B) Loss of the mutant allele (Is this correct option)
C) A stable equilibrium maintaining both alleles
D) An unstable equilibrium with possible fixation or loss of either allele

2. Average polymorphism (heterozygosity) within a species at a particular gene region is expected to be?
A) 2µ
B) 1/(2N)
C) 4Nµ (Is this correct option?)
D) 2N
E) 2Nµ

3. The chance of coalescence of two lineages of a locus each generation is?
A) 2µ
B) 1/(2N) (Is this correct option?)
C) 4Nµ
D) 2N
E) 2Nµ

4. The average time to coalescence of two lineages is how many generations?
A) 2µ
B) 1/(2N)
C) 4Nµ
D) 2N (Is this correct option?)
E) 2Nµ

5. The divergence expected between species for a gene is?
A) 2µ
B) 1/(2N)
C) 4Nµ (Is this correct option?)
D) 2N
E) 2Nµ

6. What is the expected allele frequency in the next generation?
A) w¯A=w¯B
B) p '= pw¯p/¯w (Is this correct option?)
C) wAA<wAB>wBB
D) wA<¯w

7. Which represents the equilibrium value?
A) w¯A=w¯B (Is this correct option?)
B) p '= pw¯p/¯w
C) wAA<wAB>wBB
D) wA<¯w

8. Which represents overdominance?
A) w¯A=w¯B
B) p '= pw¯p/¯w
C) wAA<wAB>wBB (Is this correct option?)
D) wA<¯w

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