'Silicon Valley' Fame Thomas Middleditch To Lead Chuck Lorre's 'B Positive'

Having the absolutely fantastic Thomas Middleditch of Silicon Valley fame coming in to lead a show that is being created by sitcom king, Chuck Lorre is the kind of match that seems to be made in heaven.

According to The Hollywood Reporter, Middleditch will lead the comedy, B Positive from mega-producer Chuck Lorre. He joins Annaleigh Ashford, Kether Donohue and Sara Rue in the cast.

Middleditch will play Drew, a recently divorced father who's in need of a kidney donor. At the end of his rope, Drew runs into Gina (Ashford, Masters of Sex), a rough-around-the-edges woman from his past who offers her kidney. The two form an unlikely bond and begin a journey that will change both of their lives.

Drew is a therapist who makes his living trying to fix other people's problems. Educated, bookish and neurotic, he lacks social skills and isn't much of a people person. Frequent Lorre collaborator Rue plays his ex-wife, Julia, and Donohue (You're the Worst) will play a "party girl" named Leanne.

Marco Pennette (Mom) wrote the multi-camera B Positive and executive produces with Lorre. The Warner Bros. TV project is one of two pilots Lorre has at CBS this season, along with United States of Al, about the friendship between a Marine veteran (Parker Young) and his unit's Afghan translator (Adhir Kalyan), who has recently moved to the United States.

The pilots will seek to join two other Lorre shows, Mom and Young Sheldon, on CBS' 2020-21 schedule.